BIOCRATES Life Sciences AG is a leading biotechnology company focused on biomarker discovery and development of in vitro diagnostics (IVDs) for early disease detection and progression in areas such as endocrinology, diabetes, nephrology, and oncology. Biocrates believes that, due to its high quality performance, mass spectromentry (MS) will come to play an increasingly important role in laboratory medicine. Biocrates considers itself to be in a unique position of becoming the leading provider of MS-Based standardized IVDs with unprecedented accuray, precision, and multiplexing potential, which will help to revolutionize the way perswonalized medicine is applied in practice.
From only 10 µL of human plasma/serum or mouse plasma
19 mouse specific bile acids
16 human specific bile acids
Ready to use components for all major ms-platforms with standard ESI ion source
Robust, fast, simple and reliable sample preparation on 96-well patended filter plate
UHPLC: 14 hours (2 hours sample prep + 10 hours LC-MS/MS + 2 hours data processing)
HPLC: 24 hours (2 hours sample prep + 20 hours LC-MS/MS + 2 hours data processing)
Human plasma, human serum and mouse plasma
(other matrix in development)
Validated in accordance with EMA guidelines
The assay has been rigorously validated in accordance with European Medicines Agency (EMA) guidelines. Proficiency testing carried out in 10 different laboratories has demonstrated the kit’s excellent accuracy (85% to 115%) and precision (coefficient of variation < 20% for all target bile acids). The Kit is intended for research use only.
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